Measuring exposures to glycol ethers.

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Measuring exposures to glycol ethers.

In 1981, NIOSH began investigating the potential reproductive health effects resulting from exposures to a class of organic solvents known generically as glycol ethers (GE). This research was begun as a result of the NIOSH criteria document development program which revealed little data available on the health effects of glycol ether exposure. Toxicologic research was begun by NIOSH and other r...

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Occupation and male infertility: glycol ethers and other exposures.

OBJECTIVES To investigate the relation between male infertility and occupational exposures, particularly glycol ethers. METHODS A case-referent study was designed in which men attending 14 fertility clinics in 11 centres across the UK in 1999-2002 were recruited following 12 months of unprotected intercourse and without a previous semen analysis. Cases were those with low motile sperm concent...

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Glycol Ethers and Neurodevelopment: Investigating the Impact of Prenatal Exposures

Glycol ethers have been widely used since the 1960s as solvents and stabilizers in a variety of personal, household, and industrial products. A new study in Environmental Health Perspectives provides some of the first evidence of associations between prenatal exposures to glycol ethers and cognitive impairments in children.These chemicals are generally valued for their low acute toxicity. Howev...

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Genotoxicity of glycol ethers.

The genetic toxicology of glycol ethers is reviewed. Ethylene glycol monomethyl ether (EGME) and diglyme have been more extensively studied than other members of this series. Most results indicate a lack of genotoxic potential, but certain tests have yielded positive responses with certain compounds. Ethylene glycol monoethyl ether (EGEE) induced sister chromatid exchanges and chromosomal aberr...

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Occupational exposure to glycol ethers and ovarian function.

T he simultaneously hydrophilic and lipophilic properties of glycol ethers account for their use as solvents in a wide range of industrial and domestic products, including paints, varnishes, cleaning agents, and cosmetics. These dozens of compounds are grouped into two main classes: ethylene glycol ethers (EGEs) and propylene glycol ethers (PGEs). Because animal experiments show several EGEs to...

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ژورنال

عنوان ژورنال: Environmental Health Perspectives

سال: 1984

ISSN: 0091-6765,1552-9924

DOI: 10.1289/ehp.845791